Ancestry
Getting Genetic Ancestry Right for Science and Society, Anna C. F. Lewis, Santiago J. Molina, Paul S Appelbaum, Bege Dauda, Anna Di Rienzo, Agustin Fuentes, Stephanie M. Fullerton, Nanibaa’ A. Garrison, Nayanika Ghosh, Evelynn M. Hammonds, David S. Jones, Eimear E. Kenny, Peter Kraft, Sandra S.-J. Lee, Madelyn Mauro, John Novembre, Aaron Panofsky, Mashaal Sohail, Benjamin M. Neale, Danielle S. Allen, Science, Vol 376, Issue 6590, pp. 250-252 2022
- My piece in STAT gives a lay person’s summary: Substituting genetic ancestry for race in research? Not so fast
- And a piece from Matilda Handsley-Davis in COSMOS Magazine: Who’s afraid of genetic ancestry?
- And a piece by Ashley Smart for Undark magazine, A Field at a Crossroads: Genetics and Racial Mythmaking
A scoping review of guidelines for the use of race, ethnicity, and ancestry reveals widespread consensus but also points of ongoing disagreement, Madelyn Mauro, Danielle S. Allen, Bege Dauda, Santiago J. Molina, Benjamin M. Neale, Anna C. F. Lewis, American Journal of Human Genetics, Vol 109, pp2110–2125, 2022
Ancestry: how researchers use it, and what they mean by it, Bege Dauda, Santiago J. Molina, Danielle S. Allen, Agustin Fuentes, Nayanika Ghosh, Madelyn Mauro, Benjamin M. Neale, Aaron Panofsky, Mashaal Sohail, Sarah R. Zhang , Anna C. F. Lewis, Frontiers in Genetics, Vol 14, 2023
Polygenic risk scores
Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization, Anna C. F. Lewis, Emma F. Perez, Anya E. R. Prince, Hana R. Flaxman, Lizbeth Gomez, Deanna G. Brockman, Paulette D. Chandler, Benjamin J. Kerman, Matthew S. Lebo, Jordan W. Smoller, Scott T. Weiss, Carrie L. Blout Zawatksy, James B. Meigs, Robert C. Green, Jason L. Vassy & Elizabeth W. Karlson, Genome Medicine, 14, Article number: 114 (2022)
Development of a clinical polygenic risk score assay and reporting workflow, Limin Hao, Peter Kraft, Gabriel F. Berriz, Elizabeth D. Hynes, Christopher Koch, Prathik Korategere V Kumar, Shruti S. Parpattedar, Marcie Steeves, Wanfeng Yu, Ashley A. Antwi, Charles A. Brunette, Morgan Danowski, Manish K. Gala, Robert C. Green, Natalie E. Jones, Anna C. F. Lewis, Steven A. Lubitz, Pradeep Natarajan, Jason L. Vassy & Matthew S. Lebo, Nature Medicine, 2022, https://doi.org/10.1038/s41591-022-01767-6
Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps, Polygenic Risk Score Task Force* of the International Common Disease Alliance, Nature Medicine, 27, p 1876–1884, 2021
Polygenic risk scores in the clinic: Translating risk into action, A C F Lewis, R C Green, J L Vassy, HGG Advances, 2 (4), 2021
Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues, A. C. F. Lewis and R. C. Green, 13:14, Genome Medicine, doi: 10.1186/s13073-021-00829-7, 2021
Genetic discrimination
The Problems with Patchwork: State Approaches to Regulating Insurer Use of Genetic Information, J. Anderson, A. C. F. Lewis, A. E. R. Prince, DePaul Journal of Health Care Law, 2(1), 2021
Long-awaited progress in addressing genetic discrimination in the United States, A. C. F. Lewis, R. C. Green & A. E. R. Prince, Genetics in Medicine, (2020)
CRISPR
Regulating Genetic Advantage, S Polcz, A Lewis, Harvard Journal of Law & Technology, 32 (1), 265-297 (2018)
- Should we regulate genetic advantage? (a blog piece)
A Menagerie of Moral Hazards: Regulating Genetically Modified Animals, S. Polcz, A Lewis, Journal of Law and Medical Ethics, 46 (1), 180-184 (2018) (Available on SSRN here)
CRISPR-Cas9 and the Non-Germline Non-Controversy, S Polcz, A Lewis, Journal of Law and the Biosciences 3, 413 (2016)
Other
An international policy on returning genomic research results, Anna C F Lewis, Bartha Maria Knoppers, Robert C Green, Genome Medicine, 13 (115), 2021
Where Bioethics Meets Machine Ethics, Anna C. F. Lewis, American Journal of Bioethics, 20:11, 22-24, DOI: 10.1080/15265161.2020.1819471 (2020)
Blogs
A Narrow Path for Optimism that Social Genomics Can Combat Inequality, Bioethics Forum, Nov 23 2020
Caster Semenya’s case gives a concrete opportunity to challenge the binary
Gay genes, liberals, and the relevance of biology to politics
A few opinion pieces from my All The Coolest Genomics blog
- What next for human germline editing?
- Some thoughts on the recommendation to “proceed with caution” on human germline modification
- Lulu and Nana: the children who will help change our morals
- Our posthuman future
Podcasts
The Genetics Podcast, https://thegeneticspodcast.fireside.fm/67, “EP67: Dr Anna Lewis from the Edmond J. Safra Center for Ethics at Harvard, on the biggest ethical questions in DNA sequencing and editing”
Channel Africa’s African Dialogue, “Artificial Intelligence in the Health sector”, https://omny.fm/shows/african-dialogue/artificial-intelligence-in-the-health-sector
Genetically Speaking, “Addressing genetic discrimination in the USA”, https://learning.ashg.org/products/paper-chat-addressing-genetic-discrimination-in-the-usa
Other papers
I have published various science papers, list available on my google scholar page.
Anna C F Lewis 